Unsaturated Iron Binding Capacity Calculator

Unsaturated Iron Binding Capacity Calculator

Here’s a comprehensive table summarizing all you need to know about Unsaturated Iron Binding Capacity (UIBC):

CategoryDetails
DefinitionUIBC measures the reserve capacity of transferrin not yet bound to iron. It indicates the amount of transferrin available for iron binding.
Clinical SignificanceElevated UIBC levels indicate iron deficiency or malabsorption; low levels may suggest iron overload.
Normal RangeGenerally 255-450 μg/dL for adults, though ranges may vary by lab standards.
InterpretationUIBC is used in conjunction with other iron tests to diagnose conditions like iron deficiency anemia or iron overload.
Relationship to TIBCTIBC (Total Iron Binding Capacity) = UIBC + Serum Iron.
Elevated UIBC CausesIron deficiency anemia, pregnancy (late stage), oral contraceptive use.
Low UIBC CausesHemolytic anemia, hypoproteinemia, inflammation, liver disease, malnutrition, pernicious anemia, sickle cell anemia.
Test PreparationFasting for 8 hours before the test is typically required.
Test ProcedureBlood draw from a vein, usually from the arm.
Related TestsSerum iron, transferrin saturation, ferritin.
Factors Affecting ResultsRecent iron supplementation, blood transfusions, certain medications.

This table provides a concise overview of UIBC, including its definition, clinical significance, normal range, interpretation, relationship to other iron tests, causes of abnormal levels, test preparation, procedure, and related factors. It’s important to note that UIBC is typically part of a broader iron panel used to assess iron status in the body.

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